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1

Directed evolution of Alcaligenes faecalis nitrilase

Ulrike Schreiner, Bianca Hecher, Sascha Obrowsky, Kerstin Waich, Norbert Klempier, Georg Steinkellner, Karl Gruber, J. David Rozzell, Anton Glieder, Margit Winkler

Journal:

Enzyme and Microbial Technology

Year:

2010

Language:

english

File:

PDF, 266 KB

english, 2010

2

A practical synthesis of 5-functionalized thieno[2,3-d]pyrimidines

Wilding, Birgit, Faschauner, Stefan, Klempier, Norbert

Journal:

Tetrahedron Letters

Year:

2015

Language:

english

File:

PDF, 307 KB

english, 2015

3

Nitrilase-Catalyzed Enantioselective Synthesis of Pyrrolidine- and Piperidinecarboxylic Acids

Margit Winkler, Dorith Meischler, Norbert Klempier

Journal:

Advanced Synthesis & Catalysis

Year:

2007

Language:

english

File:

PDF, 93 KB

english, 2007

4

ChemInform Abstract: Enzyme-Catalyzed Formation of (S)-Cyanohydrins Derived from Aldehydes and Ketones in a Biphasic Solvent System.

Herfried Griengl, Norbert Klempier, Peter Poechlauer, Michael Schmidt, Nongyuan Shi, Antonia A. Zabelinskaya-Mackova

Journal:

Year:

1999

File:

PDF, 30 KB

1999

5

Selective Biotransformation of Substituted Alicyclic Nitriles by Rhodococcus equi A4.

Ludmila Martinkova, Norbert Klempier, Margit Preiml, Maria Ovesna, Marek Kuzma, Veronika Mylerova, Vladimir Kren

Journal:

Year:

2002

File:

PDF, 29 KB

2002

6

A New Approach to β-Amino Acids: Biotransformation of N-Protected β-Amino Nitriles.

Margit Preiml, Kerstin Hillmayer, Norbert Klempier

Journal:

Year:

2003

File:

PDF, 102 KB

2003

7

ChemInform Abstract: Nitrilase and Nitrile Hydratase Catalyzed Enantioselective Preparation of Non-Proteinogenic Amino Acids

Norbert Klempier, Margit Winkler

Journal:

Year:

2010

File:

PDF, 11 KB

2010

8

Influence of relative configuration of disubstituted cyclopentanes and -hexanes on 13C shifts

Margit Winkler, Norbert Klempier, Hansjörg Weber, Katrin R. Grünwald, Michaela Flock, Alk Dransfeld

Journal:

Magnetic Resonance in Chemistry

Year:

2008

Language:

english

File:

PDF, 257 KB

english, 2008

9

Preparation of optically active cyanohydrins using the (S)-hydroxynitrile lyase from Hevea brasiliensis

Michael Schmidt, Stephanie Hervé, Norbert Klempier, Herfried Griengl

Journal:

Year:

1996

Language:

english

File:

PDF, 546 KB

english, 1996

10

Synthesis of α,β-unsaturated (S)-cyanohydrins using the oxynitrilase from Hevea brasiliensis

Norbert Klempier, Ulrike Pichler, Herfried Griengl

Journal:

Tetrahedron: Asymmetry

Year:

1995

Language:

english

File:

PDF, 240 KB

english, 1995

11

Synthesis and microbial transformation of β-amino nitriles

Margit Winkler, Ludmila Martínková, Astrid C. Knall, Stefan Krahulec, Norbert Klempier

Journal:

Year:

2005

Language:

english

File:

PDF, 345 KB

english, 2005

12

Glycol and olefin electrophoric release tags

Samy Abdel-Baky, Norbert Klempier, Roger W. Giese

Journal:

Year:

1990

Language:

english

File:

PDF, 1.11 MB

english, 1990

13

Enzyme catalysed formation of (S)-cyanohydrins derived from aldehydes and ketones in a biphasic solvent system

Herfried Griengl, Norbert Klempier, Peter Pöchlauer, Michael Schmidt, Nongyuan Shi, Antonina A Zabelinskaja-Mackova

Journal:

Year:

1998

Language:

english

File:

PDF, 565 KB

english, 1998

14

Aliphatic (S)-cyanohydrins by enzyme catalyzed synthesis

Norbert Klempier, Herfried Griengl, Marianne Hayn

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 247 KB

english, 1993

15

A new approach to β-amino acids: biotransformation of N-protected β-amino nitriles

Margit Preiml, Kerstin Hillmayer, Norbert Klempier

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 79 KB

english, 2003

16

Asymmetric hydrolysis of epoxides using an immobilized enzyme preparation from Rhodococcus sp.

Petra Hechtberger, Gernot Wirnsberger, Martin Mischitz, Norbert Klempier, Kurt Faber

Journal:

Tetrahedron: Asymmetry

Year:

1993

Language:

english

File:

PDF, 279 KB

english, 1993

17

Biocatalytic preparation of bicyclo[3.2.0]heptane derivatives

Norbert Klempier, Paul Geymayer, Peter Stadler, Kurt Faber, Herfried Giengl

Journal:

Tetrahedron: Asymmetry

Year:

1990

Language:

english

File:

PDF, 497 KB

english, 1990

18

Chemoenzymatic large-scale preparation of homochiral bicyclo[3.2.0]hept-2-en-6-one

Norbert Klempier, Kurt Faber, Herfried Griengl

Journal:

Biotechnology Letters

Year:

1989

Language:

english

File:

PDF, 191 KB

english, 1989

19

Enantioseparation of nonproteinogenic amino acids

Margit Winkler, Norbert Klempier

Journal:

Analytical and Bioanalytical Chemistry

Year:

2009

Language:

english

File:

PDF, 176 KB

english, 2009

20

Selective transformation of nitriles into amides and carboxylic acids by an immobilized nitrilase

Norbert Klempier, Anna de Raadt, Kurt Faber, Herfried Griengl

Journal:

Tetrahedron Letters

Year:

1991

Language:

english

File:

PDF, 230 KB

english, 1991

21

Chemoselective biotransformation of nitriles by Rhodococcus equi A4

Ludmila Martínková, Norbert Klempier, Irena Prepechalov´, Vera Prikrylová, Mária Ovesná, Herfried Griengl, Vladimír Kren

Journal:

Biotechnology Letters

Year:

1998

Language:

english

File:

PDF, 143 KB

english, 1998

22

ChemInform Abstract: Preparation of Optically Active Cyanohydrins Using the (S)- Hydroxynitrile Lyase from Hevea brasiliensis.

M. SCHMIDT, S. HERVE, N. KLEMPIER, H. GRIENGL

Journal:

Year:

1996

File:

PDF, 32 KB

1996

23

Enzymatic hydrolysis of heterocyclic nitriles

Norbert Klempier, Anna De Raadt, Herfried Griengl, Gottfried Heinisch

Journal:

Journal of Heterocyclic Chemistry

Year:

1992

File:

PDF, 220 KB

1992

24

Biotransformation of β-amino nitriles: the role of the N-protecting group

Margit Preiml, Helmut Hönig, Norbert Klempier

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2004

Language:

english

File:

PDF, 94 KB

english, 2004

25

Biocatalytic application of nitrilases from Fusarium solani O1 and Aspergillus niger K10

Margit Winkler, Ondřej Kaplan, Vojtěch Vejvoda, Norbert Klempier, Ludmila Martínková

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2009

Language:

english

File:

PDF, 201 KB

english, 2009

26

Biotransformation of 3-substituted methyl (R,S)-4-cyanobutanoates with nitrile- and amide-converting biocatalysts

Ludmila Martı́nková, Norbert Klempier, Joseph Bardakji, Andreas Kandelbauer, Mária Ovesná, Tereza Podařilová, Marek Kuzma, Irena Přepechalová, Herfried Griengl, Vladimı́r Kren

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2001

Language:

english

File:

PDF, 89 KB

english, 2001

27

Nitrilases Catalyze Key Step to Conformationally Constrained GABA Analogous γ-Amino Acids in High Optical Purity

Winkler, Margit, Knall, Astrid C., Kulterer, Martin R., Klempier, Norbert

Journal:

Journal of Organic Chemistry

Year:

2007

Language:

english

File:

PDF, 66 KB

english, 2007

28

Nitrile Reductase from Geobacillus kaustophilus: A Potential Catalyst for a New Nitrile Biotransformation Reaction

Wilding, Birgit, Winkler, Margit, Petschacher, Barbara, Kratzer, Regina, Glieder, Anton, Klempier, Norbert

Journal:

Advanced Synthesis & Catalysis

Year:

2012

Language:

english

File:

PDF, 225 KB

english, 2012

29

Targeting the Substrate Binding Site of E. coli Nitrile Reductase QueF by Modeling, Substrate and Enzyme Engineering

Wilding, Birgit, Winkler, Margit, Petschacher, Barbara, Kratzer, Regina, Egger, Sigrid, Steinkellner, Georg, Lyskowski, Andrzej, Nidetzky, Bernd, Gruber, Karl, Klempier, Norbert

Journal:

Chemistry - A European Journal

Year:

2013

Language:

english

File:

PDF, 410 KB

english, 2013

30

Unconventional substrates for enzymatic reduction: carboxylates and nitriles

Winkler, M., Napora-Wijata, K., Wilding, B., Klempier, N.

Journal:

New Biotechnology

Year:

2014

Language:

english

File:

PDF, 125 KB

english, 2014

31

Determination of polycyclic aromatic hydrocarbons in soot by mass spectrometry with direct sample insertion

Klempier, Norbert., Binder, Heinrich.

Journal:

Analytical Chemistry

Year:

1983

Language:

english

File:

PDF, 1011 KB

english, 1983

32

A mild and simple enzymic conversion of aldono- and aldurononitriles into the corresponding amides and/or carboxylic acids

de Raadt, Anna, Griengl, Herfried, Klempier, Norbert, Stuetz, Arnold E.

Journal:

Journal of Organic Chemistry

Year:

1993

Language:

english

File:

PDF, 777 KB

english, 1993

33

Chemoselective enzymatic hydrolysis of aliphatic and alicyclic nitriles

de Raadt, Anna, Klempier, Norbert, Faber, Kurt, Griengl, Herfried

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1992

Language:

english

File:

PDF, 563 KB

english, 1992

34

Enzyme stabilizer DTT catalyzes nitrilase analogue hydrolysis of nitriles

Winkler, Margit, Glieder, Anton, Klempier, Norbert

Journal:

Chemical Communications

Year:

2006

Language:

english

File:

PDF, 229 KB

english, 2006

35

Selective biotransformation of substituted alicyclic nitriles by Rhodococcus equi A4

Martínková, Ludmila, Klempier, Norbert, Preiml, Margit, Ovesná, Mária, Kuzma, Marek, Mylerová, Veronika, Kren, Vladimír

Journal:

Canadian Journal of Chemistry

Year:

2002

Language:

english

File:

PDF, 71 KB

english, 2002

36

Useful hydrolytic enzymes: Proteases, lipases and nitrilases

Berger, Brigitte, de Raadt, A., Griengl, Herfried, Hayden, Walter, Hechtberger, Petra, Klempier, Norbert, Faber, K.

Journal:

Pure & Applied Chemistry

Year:

1992

Language:

english

File:

PDF, 289 KB

english, 1992

37

An investigation of nitrile transforming enzymes in the chemo-enzymatic synthesis of the taxol sidechain

Wilding, Birgit, Veselá, Alicja B., Perry, Justin J. B., Black, Gary W., Zhang, Meng, Martínková, Ludmila, Klempier, Norbert

Journal:

Organic & Biomolecular Chemistry

Year:

2015

Language:

english

File:

PDF, 1.88 MB

english, 2015

38

Biocatalytic Preparation of Enantiomerically Pure endo -Bicyclo[3.3.0]oct-7-en-2-ol

Klempier, Norbert, Faber, Kurt, Griengl, Herfried

Journal:

Year:

1989

File:

PDF, 175 KB

1989

39

A convenient synthetic route to substituted pyrrolo[2,3-b]pyridines via a novel ethylene-bridged compound

Wilding, Birgit, Vidovic, Carina, Klempier, Norbert

Journal:

Tetrahedron Letters

Year:

2015

Language:

english

File:

PDF, 387 KB

english, 2015

40

Back Cover: Targeting the Substrate Binding Site of E. coli Nitrile Reductase QueF by Modeling, Substrate and Enzyme Engineering (Chem. Eur. J. 22/2013)

Wilding, Birgit, Winkler, Margit, Petschacher, Barbara, Kratzer, Regina, Egger, Sigrid, Steinkellner, Georg, Lyskowski, Andrzej, Nidetzky, Bernd, Gruber, Karl, Klempier, Norbert

Journal:

Chemistry - A European Journal

Year:

2013

File:

PDF, 686 KB

2013

41

ChemInform Abstract: A Practical Synthesis of 5-Functionalized Thieno[2,3-d]pyrimidines.

Wilding, Birgit, Faschauner, Stefan, Klempier, Norbert

Journal:

Year:

2015

File:

PDF, 18 KB

2015

42

ChemInform Abstract: Biocatalytic Preparation of Bicyclo(3.2.0)heptane Derivatives.

KLEMPIER, N., GEYMAYER, P., STADLER, P., FABER, K., GRIENGL, H.

Journal:

Year:

1990

File:

PDF, 195 KB

1990

43

Kinetic analysis and probing with substrate analogues of the reaction pathway of the nitrile reductase QueF from Escherichia coli

Jung, Jihye, Czabany, Tibor, Wilding, Birgit, Klempier, Norbert, Nidetzky, Bernd

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 2.67 MB

english, 2016

44

Newest Developments in the Preparation of Thieno[2,3- d ]pyrimidines

Wilding, B., Klempier, N.

Journal:

Organic Preparations and Procedures International

Year:

2017

Language:

english

File:

PDF, 1.88 MB

english, 2017